Background: The use of intramedullary nail fixation to treat surgically treated proximal humeral fractures has grown in acceptance and interest. Diaphyseal fractures of the humerus are frequent, making up between three and five percent of all fractures. Therefore, the purpose of the current study was to determine if interlocking nails are effective in treating adult patients with diaphyseal fractures of the humerus.

Materials and Methods: The study comprised 40 patients in all who met the eligibility requirements. For the first three months after the fracture union, all patients were monitored monthly. After that, they were followed up every two months until the study's conclusion. They underwent a thorough clinical examination, with particular attention paid to the range of motion in the shoulders and elbows as well as any subjective symptoms.

Results: The study's conclusion included an analysis of the general findings. 18 patients had Excellent results, 9 patients had good results, and 3 patients had poor results. 8 patients had associated fractures along with the humerus fracture.