Introduction: Hand and wrist wounds are breaches of the skin barrier caused by a harmful agent. The aim is to describe the epidemiological, clinical, therapeutic, and evolutionary profile.

Patients and Method: This was a prospective descriptive study, conducted from January 2020 to June 2022, including all traumatic wounds (hand and/or wrist). The variables studied were epidemiological, clinical, therapeutic, and developmental.

Results: Out of 280 traumatic wounds received, we collected 44 hand and/or wrist wounds, representing 15.7%. The average age was 33.2 years [18-78 years] with a male predominance (sex ratio: 4.5). The etiological circumstances were dominated by assaults (45.5%) and traffic accidents (45.5%). Bladed weapons were used as injuring agents in 45.4% of cases. Motorcycle taxi drivers accounted for 56.8% of cases. The most frequent lesion location was the palm of the hand (59%) and the right side (52.3%). Tendon injuries were observed in 29 cases (65.9%), bone injuries in 25 cases (38.63%), nerve injuries in 8 cases (15.9%), and vascular injuries in 7 cases (13.63%). A sequela in the form of amputation was found in 8 patients, representing 18.18% of cases. The average time to return to work was 147 days; functional outcomes were rated as excellent in 22.8% (n=10) and good in 41% (n=18) of cases.