Introduction: Fracture lateral end of clavicle and Acromioclavicular (AC) joint disruption have been managed by various direct and indirect surgical methods. The restoration of the coracoclavicular interspace is of utmost importance to maintain the stability around the acromioclavicular joint and to prevent recurrence of the deformity. This retrospective study compared the results of fixation of fracture lateral end clavicle and AC joint dislocation using double endobutton loop fixation. Methods: This study is conducted at a tertiary care trauma center in December 2020. The clinical and radiological data of all patients with Neer type II lateral clavicle fractures and Rockwood type V AC joint dislocations (both fresh injuries and neglected) who had undergone fixation using double endobutton technique between January 2016 to December 2020 were reviewed. CONSTANT score and UCLA shoulder rating scale for functional outcome with at least 1 year of follow up were evaluated and compared. Results: Ten patients with Neer type II fracture lateral end clavicle and eight patients with Rockwood grade V AC joint disruption were included in this study. The average age of patients in the study was 39.89 ± 9.95 years with 14 male and 4 female patients. The average duration from time of injury to surgery was 5.44 ± 1.2 days and the average duration of surgery was 55.33 ± 7.24 mins. The mean CONSTANT shoulder score was 88 ± 6.56 and the UCLA shoulder rating scale was 31.06 ± 2.1 for the study group. Conclusion: Open double endobutton loop system is a suitable fixation method for fracture lateral end clavicle (Neer type II) and also for AC joint disruption (grade V) with satisfactory functional outcome. It also avoids the hardware related problems which are commonly encountered in rigid fixation systems warranting implant removal after sometime. More prospective studies are required for evaluation of outcomes of this technique.