Health outcomes in elderly individuals with acute severely painful osteoporotic vertebral compression fractures
Terrence Diamond, William Clark, Paul Bird, Peter Gonski, Elizabeth Barnes, Val Gebski
There are minimal data describing outcomes after acute clinical osteoporotic vertebral compression fractures (OVCF). We report on pain scores, quality of life measures, complication and specific osteofragility risk factors in the placebo-treated individuals (n=59) in the VAPOUR study. By 6 months, three individuals (5%) withdrew, three (5%) had died, two (4%) had developed spinal cord compression and two (5%) had sustained new OVCF’s. Mean baseline fracture compression of 46% of height loss had increased to 63%. Despite overall improvements, 27 (53%) had ongoing problematic back pain (numeric rating scale > 4) and 32 (63%) had significant disability (Roland Morris Questionnaire > 10) at 6-months. 44 (75%) were considered high risk for recurrent OVCF. These data confirm that elderly individuals with acute severely painful clinical OVCF treated with usual care, demonstrate adverse outcomes even at 6 months after fracture. Further research should focus on optimal treatments for this high-risk cohort. (Word count 150).
Terrence Diamond, William Clark, Paul Bird, Peter Gonski, Elizabeth Barnes, Val Gebski. Health outcomes in elderly individuals with acute severely painful osteoporotic vertebral compression fractures. International Journal of Orthopaedics Research, Volume 2, Issue 4, 2020, Pages 22-27