Bone defects arising from non-ossifying fibroma may render the affected bone mechanically weak especially when associated with larger defect size in a growing skeleton of an active child. Most of these defects are asymptomatic and are incidental findings with very few presenting with pathological fractures. They can however be satisfactorily managed by conservative or operative means as per the case and personality of fracture. These lesions affecting a larger segment of bone at multiple skeletal sites is a rare occurrence. Simultaneous fractures of both bones of leg and femur or floating knee injury pattern, in association with polyostotic non-ossifying fibroma, has not been reported the best knowledge of the authors.