A randomized control trial to gauge the efficacy of leucocyte rich platelet rich plasma (LR-PRP) injection versus local corticosteroid injection in treatment of plantar fasciitis
Sharat Balemane, Preetish Endigeri, Harshavardhan BR, Abdul Rahman
Introduction: Heel pain due to plantar fasciitis is a common problem which leads to a significant morbidity and belittled quality of life. Various treatment ways have been tried in dealing with this problem with varying efficacy rates. The current study was planned to evaluate the efficacy of Leucocyte rich platelet rich plasma (LR-PRP) injections when compared to traditional therapy with corticosteroid injections in patients with plantar fasciitis. Methods: Patients with a history of plantar fasciitis were block randomized into 2 groups (n=30 in each). The first group was subjected to Leucocyte rich platelet rich plasma injections whereas the other underwent corticosteroid injections. The patients were followed up for 6 months at intervals of 1, 4, 12 weeks and at the end of 6 months the treatment outcome was evaluated using visual analogue score and Nirschl staging system. Results: At the end of 6 months 46.66% patients in corticosteroid injection group and 90% patients in LR-PRP group were completely relieved of pain. The duration for maximum benefit to reach is longer in LR-PRP (11.43weeks) compared to corticosteroid injection (6.1 weeks). Discussion: Patients on Leucocyte rich platelet rich plasma demonstrated a statistically significant decrease in pain compared to corticosteroid injection group on 6 month follow up. It can be concluded that LR-PRP does seem to provide an alternative treatment strategy providing better pain relief in patients with plantar fasciitis on a long-term basis with minimal side effects.